Office Location: Wohl Clinic Building, 5th Floor
660 S. Euclid Ave.
Campus Box 8127
St. Louis, MO 63110
Lab Phone: (314)747-0084
Fax: (314) 747-3963
E-mail Address: firstname.lastname@example.org
I am originally from Romania, born and raised in Transilvania. I attended Medical School in my hometown, Cluj Napoca. In the summer of 2003, I moved to the US and I have lived in Chicago since. I completed my Internal Medicine Residency at Advocate Lutheran General Hospital followed by a Chief Residency year at West Suburban Medical Center before starting my Endocrinology and Metabolism Fellowship at Washington University in Saint Louis.
There is no consensus regarding optimal peri-operative steroid management of patients with pituitary adenomas or cysts undergoing pituitary surgery. Patients undergoing pituitary surgery often receive “stress” doses of glucocorticoids around the time of surgery to prevent adrenal insufficiency, but compelling data to support the routine use of peri-operative steroids are unavailable. Given the pleiotropic adverse effects of steroids, appropriately avoiding glucocorticoid use could decrease peri-operative complications. We are conducting a pilot prospective study to test the hypothesis that withholding glucocorticoids in patients with an intact hypothalamic-pituitary-adrenal (HPA) axis undergoing transsphenoidal surgery is safe.
The incidence of type 2 diabetes mellitus is increasing rapidly on a worldwide basis. Abnormalities in the islet beta cell and insulin secretion play a central role in the pathogenesis of type 2 diabetes. Based on previous studies with xenin-25, our hypothesis is that defective neural signaling to islets is the primary defect that leads to development of diabetes. We are studying the effects of xenin, GIP and GLP-1 on insulin secretion in humans.